Mixing Alcohol and Drugs Can Be Deadly
Many individuals who take illicit drugs will see alcohol as a less harmful substance. This incorrect belief leads to alcohol and drugs frequently being mixed together; the results of which can lead to addiction and can also prove to be fatal. However, substance use and drug use, especially when mixing drugs with alcohol or other drugs, significantly increases the risk of serious health complications.
Alcohol was involved in a third of all of the drug-related deaths recorded in England and Wales in 2016 by the National Office of Statistics. This gives us an insight into just how dangerous mixing alcohol with drugs is. Overdose deaths are often linked to mixing drugs, as the additive effects of combining substances can lead to increased risk of fatal outcomes. This practice is known as polydrug use, which refers to using multiple drugs, including alcohol, at the same time and significantly increases health risks.
There are certain drugs that when mixed with alcohol become extremely dangerous and unpredictable in their effects. Drugs that should NOT be mixed with alcohol under ANY circumstance include all Class A drugs, controlled prescription medications, legal highs and even many of the over the counter medications available at your local pharmacy. Alcohol and medication interactions, including with over the counter medications and commonly prescribed drugs, can have negative effects and increase the risk of harm. Drinking alcohol or choosing to drink alcohol while taking illegal drugs or other drugs increases the risk of medication interactions and overdose.
The negative effects of mixing drugs and alcohol are due to additive effects, which increases the risk of serious health consequences.
Types of Substance Interactions: Why Mixing is So Risky
When alcohol is combined with other drugs—whether they are prescription drugs, over the counter medications, or illegal drugs—the way these substances interact inside the body can be highly unpredictable and dangerous. These interactions, known as substance interactions, can amplify or alter the effects of each drug, often in ways that are difficult to anticipate.
The central nervous system is especially vulnerable to these combined effects. Alcohol acts as a depressant, slowing down brain activity and bodily functions. When mixed with other substances that also affect the central nervous system, such as sedatives, stimulants, or painkillers, the risk of overdose increases dramatically. This is because the body can become overwhelmed by the additive or even synergistic effects, leading to life-threatening complications like respiratory depression, heart failure, or loss of consciousness.
Even drugs that seem harmless on their own can become highly toxic when mixed with alcohol. Prescription drugs, for example, may interact with alcohol in ways that increase the risk of side effects, reduce the effectiveness of medications, or cause dangerous changes in blood pressure and heart rate. Illegal drugs, when combined with alcohol, can create new compounds in the body or intensify the negative effects of both substances, further increasing the risk of overdose and other serious health issues.
Ultimately, mixing alcohol with any other drug significantly increases the risk of unpredictable and potentially fatal outcomes. Understanding these risks is crucial for anyone who uses alcohol, prescription drugs, or illegal drugs, as even a single episode of mixing substances can have devastating consequences.
The Drink and Drugs Gamble
Of course, it is far safer not to take any drugs at all, but the reality is that many do. Mixing alcohol with drugs really is like playing Russian roulette with your life. Whether it is on a recreational basis, because of a medical need or because of an addiction, the following drugs should never be mixed with alcohol:
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Opiates – When opiates are mixed with alcohol, the sedative effects become much more pronounced due to additive effects. Opiates such as Class A Heroin and many prescription painkillers—including Morphine, Oxycodone, Oxycontin, Dihydrocodeine, Co-Codamol, and numerous codeine-based over-the-counter medicines—are types of opioid drug and opioid painkillers. These drugs act on the central nervous system, slowing breathing rate and increasing the risk of overdose and overdoses. Alcohol increases the sedative effects of opioid drugs, which significantly increases the risk of fatal outcomes. Alcohol and opiates together are a very deadly mix; both drugs are extremely addictive and the risk of overdose is greatly heightened.
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Cocaine – Cocaine and alcohol are often used together to achieve a euphoric state without the drunkenness or overstimulation. Consuming the two drugs together causes an independent third drug to be produced by the liver called cocaethylene; this drug is known as Cocaethylene. Cocaethylene is a longer acting drug than just cocaine. Together, alcohol and cocaine produce a long-lasting intoxicated but functional high. Independently, both alcohol and cocaine are known to be very addictive; when cocaethylene is produced, the risks of addiction developing are even more prevalent. Some studies suggest that consuming alcohol and cocaine together carries an 18 to 25 fold increased chance of immediate death than cocaine alone. It is also far more toxic and potent to the body’s organs, especially the heart and liver, and increases the risk of liver damage and liver disease. Those that mix the two together will have a capacity to drink far more alcohol than they normally would without cocaine; again, this carries additional risks of damage to the body’s organs as can often result in dangerous levels of binge drinking and cocaine consumption.
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Benzodiazepines – Benzodiazepines are a prescription only sedative medication that offer therapeutic and medical benefits to the patient. As well as causing sedation they also have the effect of a false sense of well being. For this reason, they are often abused and used recreationally. When Benzodiazepines are mixed with alcohol they become very dangerous. Alcohol increases the risk of negative effects such as respiratory depression and overdose. The sedative effects are vastly increased and often cause the user to “black out” (continue to function but not be able to recall events the next day due to over intoxication). The increased sedative effects and a false sense of courage and power put the user at high risk of harming themselves or others. There is also the increased danger of overdose, coma and respiratory failure.
Mixing alcohol with certain medications, such as aspirin, can also increase the risk of gastrointestinal bleeding, especially in older adults.
Mixing stimulants (such as amphetamines or cocaine) with alcohol increases the risk of panic attacks, heart problems, and other negative effects. Additionally, combining alcohol with certain drugs that affect serotonin levels, such as some antidepressants or stimulants, can increase the risk of serotonin syndrome, a potentially life-threatening condition.
Combining alcohol with magic mushrooms can lead to unpredictable effects and heightened risks.
In summary, mixing alcohol with other drugs can compromise the immune system and increases the risk of serious health complications, including changes in blood pressure.
Are You Using a Deadly Mix of Alcohol and Drugs?
Those that suffer from substance addiction, will often use two or more drugs (including alcohol) for a combined effect. Multiple substance addiction is extremely dangerous; left untreated it often leads to an untimely death. Individuals with substance use disorder frequently have co-occurring mental health issues, which complicate treatment and increase health risks.
If you or a loved one are addicted to alcohol and a drug, it is vital that you seek immediate professional help. Detoxing from more than one substance, especially where alcohol is involved is often complex and considered high risk.
At Rehab Today by PCP we treat all addictions presenting simultaneously. Following a comprehensive medical assessment, a bespoke medical drug detox will be prescribed to ensure that you are able to stop the alcohol and the drugs in the safest manner possible. We also tailor our addiction recovery programmes to your individual specific treatment needs, addressing both substance use disorder and mental health for the best outcomes.
Please call us today to find out more about our affordable private alcohol and drug rehab clinics. You can also contact us by completing and returning our online self-assessment form.
Author
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Dr Otulana is PCP’s longest-serving doctor. He is an experienced Physician with Specialist Interest in Substance Misuse Management and he has a wide range of experience in the assessment and management (including detoxification) of clients with various drug and substance addiction problems. Dr Otulana started practising as a doctor in 2000 and with over 10 years as an Addiction Physician. He is an Advanced Addiction Practitioner Member of Addiction Professionals and also holds the Certificate in Clinical Psychopharmacology (Part 1) of the British Association for Psychopharmacology. He is additionally a strong healthcare services professional with a Master of Business Administration (M.B.A.) degree from Cambridge University Judge Business School.
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