Etizolam addiction can develop quickly because etizolam acts in a similar way to benzodiazepines, increasing GABA activity and leading to tolerance, dependence, and withdrawal symptoms when it is taken repeatedly or in high doses. It is a drug that very few people intentionally set out to illicitly purchase, yet end up taking anyway. Passed off on the street as Valium and other similar drugs, etizolam can be several times stronger than the diazepam it’s sold as, meaning someone can take a far bigger dose than they ever intended to.
That makes etizolam addiction a hidden and growing risk in the UK, not only because of its potency and overdose potential, but because many people do not realise they have taken it until dependency problems start to arise. For adults in the UK struggling with etizolam or similar drug misuse, as well as families trying to understand the risks and treatment options, this page explains what etizolam is, the signs of addiction to watch for, how it compares with drugs such as Xanax and Valium, the dangers of withdrawal, and how to find recovery services in the UK.
What is Etizolam?
Etizolam is a sedative drug that lives within a family known as thienodiazepines. As you can probably tell from the name, thienodiazpines, and therefore etizolam, are very close chemical cousins of benzodiazepines and drugs like diazepam and alprazolam.
It isn’t technically a benzodiazepine, but acts on the same receptors in the brain and produces very similar sedation effects. Because of this, it’s used to reduce anxiety and induce muscle relaxation.
Etizolam is licensed for use in a handful of countries, like Japan and Italy, where it’s prescribed for anxiety.1 In the UK, though, etizolam has been a Class C drug in the UK since May 2017, when it was brought under the Misuse of Drugs Act 1971 alongside a group of other designer benzodiazepines.
Is Etizolam Addictive?
Etizolam holds the same dependence risks as the benzodiazepines that it resembles and this is largely because the drug acts on the central nervous system in the same way as benzos do.
It was originally developed to treat anxiety and related sleep problems in other countries for medical purposes. It works by boosting the effects of GABA, which is the brain chemical responsible for calming activity, which then produces the sedation and relief from anxiety.3 The problem here is that with repeated and negligent use, the brain adapts to the constant presence of the drug, long-term use can alter brain chemistry, and this can increase the risk of drug addiction.
From this reliance, two main issues start to arise. The first is tolerance, where the same dose stops working and more is needed to get the same effect. The second is physical dependence, where stopping abruptly produces strong and uncomfortable withdrawal symptoms.
While there are scarce human studies on whether etizolam is more addictive than other benzodiazepines, like Xanax, the science still shows that it’s more potent by weight and shorter acting.4 In theory, these are both factors that could encourage frequent usage.
How does Etizolam compare to Xanax and Valium?
Before we begin, it’s worth noting that the following drug comparisons are only reiterating what these substances are supposed to do from a medical standpoint. If you’re using etizolam illicitly, there’s a high chance that these numbers will vary for you and, in some cases, be meaningless.
This is because illicit street drugs are cut with fillers and other psychoactive substances, meaning no one knows what tablet they’re actually swallowing. Nevertheless, it’s still worth understanding what you could be taking.
Here’s how the three compare:
| Drug | Onset (peak effect) | Half-life | Potency vs diazepam |
|---|---|---|---|
| Etizolam | 30 minutes to 2 hours | ~3 to 4 hours | ~6 to 10x |
| Alprazolam (Xanax) | 1 to 2 hours | ~11 hours | ~10x |
| Diazepam (Valium) | 30 to 90 minutes | ~20 to 70 hours | Baseline (1x) |
As we can see here, etizolam has the shortest half-life out of the three drugs mentioned, meaning it will push the user towards taking more once the effects start to wear off. Risk is also higher in people with previous addictions to other substances. Genetics can also play a role in who develops dependence more quickly.
What are the signs and symptoms of Etizolam Addiction?
Etizolam use can be hard to spot, especially as its effects can look like drunkenness and even simple tiredness. That said, if you are worried about a loved one, there are signs that are worth looking out for.
Signs of being under the influence
Heavy drowsiness
Slurred speech
Poor coordination
Unsteady on their feet
Memory loss
Potential signs that Etizolam Addiction is developing
Needing more to get the same effects
Anxiety between doses
Insomnia
Actively searching for more etizolam, either online or on the streets.
Using it to get through an ordinary day as a temporary fix, or to self medicate for anxiety
Secrecy about how much etizolam is being taken
Continued use, despite obvious negative outcomes linked to abuse
It’s also worth recognising the reason as to why we’ve split the signs into two separate sections. This is because if you notice that a loved one has potentially taken etizolam, it doesn’t automatically mean that they’re dealing with an etizolam addiction. Recreational use is very different from use that’s fueled by dependence.
Is Etizolam a problem in the UK?
Answering this question is a lot more difficult than it first sounds. With a drug like heroin, for example, the picture is relatively clear in that the people buying it are specifically looking for it. This makes demand and harm much easier to trace.
Etizolam, on the other hand, doesn’t always work that way. Many people taking it never set out to, or even know they’re taking it, which means it hides inside the market for other benzodiazepines. This makes it much harder to pinpoint as a specific problem with the drug.
That said, there are two areas that can be tracked to gain more insight into etizolam issues in the UK.
Etizolam-related deaths
We first have to turn our attention to Scotland, where the drug was behind the term “fake Xanax“. In 2012, etizolam was mentioned in a single death, but by 2020, that figure had reached 806.7 These figures reflect serious drug abuse harms tied to etizolam abuse, not just isolated incidents. This number accounted for around 60% of all drug-related deaths in Scotland in that year.
Following international controls, etizolam has been displaced by a newer designer benzodiazepine called bromazolam, which, in 2023, accounted for 426 of drug misuse deaths in Scotland. That said, it doesn’t mean etizolam disappeared from the illicit market, and it still accounted for 173 deaths in 2023.
Etizolam abuse and being sold as other drugs
Another issue the UK faces is that, on the street level, etizolam is appearing in other drug purchases unintentionally.
WEDINOS, a drug testing firm from Wales, found that only 45% of the samples thought to be diazepam actually contained it. That’s 539 out of the total, meaning 55% of the samples were something else entirely. Worryingly, 372 of these contained etizolam.
When we revert back to the comparison table shown earlier, it’s clear to see how this is a problem. If a person is buying what they think is diazepam, but in fact etizolam, the potency and half-life aspects are dramatically different.
This could lead to issues such as etizolam addiction, and worse, etizolam overdose, with the risk especially high at high doses or if it’s mixed with other substances like alcohol, where respiratory depression is a key danger.
Am I Addicted to Etizolam?
If you, or someone you care about, has been using etizolam regularly, it’s worth pausing on the relationship you have with the drug, or the drug you think you’re taking.
As the effects of etizolam are similar to other street benzodiazepines, including dependence, it can also raise wider substance use concerns that need to be understood.
Ask yourself:
Do you need more than you used to just to feel the initial effect?
Have you tried to cut down and found it too difficult?
Do you feel anxious when you haven’t taken it?
Do you keep using despite it causing problems in your life?
If you’re answering ‘yes’, even just one of these questions, it’s something that’s worth acting on now.
What to do next if you've noticed Etizolam Addiction
If you’ve noticed signs of etizolam addiction in yourself, or in someone you love, seeking help can feel daunting, but medical help is still the safest next step.
You may have all the intention in the world to quit the drug once you realise, and that’s admirable, but a big problem emerges here, and that’s the withdrawal process that etizolam causes.
Stopping etizolam abruptly can be very dangerous, and it’s not a thing to take on without support.
If you’re using etizolam, or suspect you’ve been taking it unknowingly, do not stop on your own. Contact PCP Rehab Today to speak with professionals who understand the withdrawal process and can guide you on your next steps.
Etizolam withdrawal symptoms
As we stated, etizolam withdrawal can cause worrying psychological and physical symptoms, and in some cases these can turn fatal.
Benzodiazepine-type withdrawals are one of the few withdrawals, alongside alcohol withdrawal, that can kill if not managed correctly.
If a dependency has formed and you stop abruptly, there is a chance that you may experience severe withdrawal, including seizures and, in extreme cases, hallucinations, which can turn fatal. UK clinical guidance is firm that withdrawal should be managed through gradual and supervised dose reduction rather than stopping suddenly and alone.
Alongside the threat of seizures during withdrawal, symptoms can also include:
Trembling
Sweating
Nausea
Insomnia
Rapid heart rate
Headaches
These physical symptoms can be accompanied by panic attacks, and withdrawal can worsen existing anxiety and sleep problems.
These symptoms alone are enough to derail anyone’s good intentions of quitting the drug, which is, again, why professional support is strongly recommended.
How long does Etizolam Withdrawal last?
Because etizolam clears the body quickly, withdrawal symptoms can begin sooner than with longer-acting drugs in similar categories. This could be within a day of the last dose.
The acute phase generally lasts several weeks, with some cases experiencing a slightly longer tail of symptoms.
But it must be noted that a lot of what we know about etizolam withdrawal is borrowed from benzodiazepine withdrawal generally. This means the length of withdrawal varies considerably depending on dose, how long someone has been using, what drug they’ve been using versus what they think they’ve been using, and individual factors, like current state of health.
Etizolam Addiction Treatment and getting the help you deserve
Help for etizolam addiction treatment in the UK is free and there’s more than one option.
Local NHS and council-commissioned drug services accept self-referrals, so you can approach them directly. A GP is also a good confidential starting point.
Due to the seizure risk, etizolam dependence would require a medically supervised detox. During a drug detox, you may be switched to an equivalent dose of a longer-acting benzodiazepine, like diazepam, and then undergo a gradual taper. Follow-on care should then be guided by a personalised treatment plan based on the severity of the dependence, any mental health concerns, and overall risk.
Once stable, the next part of treatment focuses heavily on the psychological side of etizolam addiction. This means undergoing evidence-based therapies to uncover the root cause of your etizolam use. Therapy can also help you manage anxiety without returning to the drug. If you were using etizolam because it was relieving symptoms of anxiety or depression, these underlying conditions can also be addressed in therapy.
Residential rehab is worth considering for heavier dependence or where attempts to detox in the community haven’t worked, and inpatient treatment commonly lasts 30 to 90 days. Outpatient programs and other forms of outpatient care can be a flexible option that lets people maintain daily responsibilities.
A residential setting could also be considered if a mental health condition sits alongside your drug use. This is because treating both together gives the best chance of long-lasting recovery. Ongoing recovery may also include relapse prevention work and support groups.
What are the next steps?
Taking in all of this at once is a lot, and you don’t need to have all the answers worked out yet. Many people reach out simply to talk things through and understand their options, without making any immediate decisions.
At PCP, that starting point is a confidential assessment that helps build a clearer picture of your situation, including your etizolam use, your wellbeing, and any risks worth addressing, so we can identify the right treatment options and shape a personalised treatment plan.
From there, the right kind of support can be discussed, whether that’s community help or a stay with us. The cost of rehab in London and other parts of the UK can be discussed.
PCP provides drug and alcohol detox and rehabilitation within a safe, CQC-registered facility in Luton, supporting people from across the UK.
If you’d like to understand what treatment looks like and whether it fits your situation, contact us today. There’s no obligation to make a decision on the call.
FAQs
Is etizolam habit forming?
Like the benzodiazepines it resembles, etizolam causes tolerance and physical dependence, so regular use leads to needing more for the same effect and to withdrawal on stopping. Dependence can develop within weeks, which is why it isn’t a drug to use casually.
Is etizolam a controlled substance? Here
Etizolam is a Class C drug in the UK, controlled under the Misuse of Drugs Act 1971 since May 2017. Possession can carry up to two years in prison, and it has never been licensed for medical use here.
Is etizolam less addictive than Xanax?
There’s no clear evidence either way. Some early animal research hints at a lower dependence risk than Xanax, but nothing in humans confirms it. Etizolam is more potent by weight and shorter-acting, both of which can encourage the frequent dosing that drives dependence.
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Dr Otulana is PCP’s longest-serving doctor. He is an experienced Physician with Specialist Interest in Substance Misuse Management and he has a wide range of experience in the assessment and management (including detoxification) of clients with various drug and substance addiction problems. Dr Otulana started practising as a doctor in 2000 and with over 10 years as an Addiction Physician. He is an Advanced Addiction Practitioner Member of Addiction Professionals and also holds the Certificate in Clinical Psychopharmacology (Part 1) of the British Association for Psychopharmacology. He is additionally a strong healthcare services professional with a Master of Business Administration (M.B.A.) degree from Cambridge University Judge Business School.
